HRD testing helps patients benefit from PARP inhibitor treatment
Product Introduction
HapOnco® PARPrion HRD Gene Testing is a gene testing product independently developed by HaploX for guiding Poly (ADP-Ribose) Polymerase Inhibitors (PARPi). The testing content includes homologous recombination repair genes such as BRCA1/2, as well as analysis of Loss of Heterozygosity (LOH), Telomeric Allelic Imbalance (TAI), and Large-Scale State Transitions (LST). It comprehensively assesses the patient's Homologous Recombination Deficiency (HRD) status and provides a reference basis for clinical PARPi treatment.
Key features
Comprehensive HRD assessment (BRCA1/2, LOH, TAI, LST).
Identifies patients potentially benefiting from PARPi therapy.
Goes beyond BRCA mutation analysis for a broader HRD evaluation.
Applicable Population
Ovarian, breast, prostate, and pancreatic cancer patients. Solid tumor patients with poor response to conventional therapies.